SelectTopGenes

Select top-ranked genes from multi-sample Pseudotimecascade results

Usage

SelectTopGenes(gene_mean_list, top = 1000)

Arguments

gene_mean_list

A multi-sample result list returned by PseudotimeMSProcess().

top

Number of top-ranked genes to select (default = 1000).

Value

A list with the same structure as gene_mean_list, but restricted to the selected top genes.

Details

This function ranks genes based on the average significance across samples. Specifically, q-values are transformed using \(-\log_{10}(q)\), and the mean transformed value across samples is used for ranking. The top top genes are selected and all corresponding components (mean expression, pattern assignment, q-values, and switch points) are subset accordingly.

Author

Zhicheng Ji, Changxin Wan, Beijie Ji